We offer bioassays developed specifically for use in biologics, best-in-class cell-based assays, and reporter vectors for use in bioassays.
A Better ADCC Bioassay
The ADCC Reporter Bioassay is ideal for quantifying Fc effector function of therapeutic antibodies, as measured by activation of NFAT signaling. The assay is based on ADCC mechanism of action, and is easier to use and less variable than classic ADCC assays.
Reporter Vectors for Bioassays
A wide choice of bioluminescent vectors to measure intracellular signaling, including predesigned vectors for cytokines, growth factors and blocker antibody drugs.
LDH Cytotoxicity Assay
The fluorescent CytoTox-ONE™ Assay rapidly measures LDH release from cells with damaged membranes. Use to quickly and easily quantify non-viable cells in multiwell plates.
Bioluminescent Cell Viability Assays
Quantifying cell viability or cytotoxicity is crucial for understanding cancer biology, compound toxicity and cellular response to cytokines. The CellTiter-Glo® and CytoTox-Glo® Assays are the industry standard for biologics testing.
A protocol for the luminescent ADCC Reporter Bioassay with provided thaw-and-use effector cells.
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