Promega Corporation

Cell Health and Metabolism

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NAD/NADH-Glo™ and NADP/NADPH-Glo™ Assays

Simple, fast and sensitive detection of nicotinamide adenine dinucleotides.

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Cell Health and Metabolism Categories

ADME Assays Our wide selection of bioluminescent enzyme substrates for proteases and metabolic enzymes such as CYPs and MAO, among others, provide powerful tools for the ADME-Tox screen.

Apoptosis Assays Get more data in less time when you multiplex cell health biomarkers. Measure one or multiple biomarkers in vitro or in situ to detect early or late events of apoptosis and get a quick status update on targeted cells.

Cell Viability Assays Promega cell viability assays allow easy measurement of the number of live cells/number of dead cells in a single well. The simple "add-mix-measure" protocols and convenient luminescent readout allow you to easily compare cell viability data from well-to-well, from plate-to-plate and from day-to-day.

Cytotoxicity Assays Promega offers multiple readouts for quantifying cytotoxicity, including luminescent and fluorescent assays that can be multiplexed with apoptosis or viability assays to help determine mechanism of cell death.

Metabolism Assays

NAD+, NADP+, NADH and NADPH are important cofactors for many enzymes involved in key cellular pathways, and quantitation of these dinucleotides is a standard approach to monitor enzyme activity directly or indirectly. Promega offers a number of systems to detect and quantify these important molecules.

Mitochondrial Function Assays A multiplexed, cell-based assay to monitor mitochondrial health. Measures ATP and a membrane integrity biomarker to distinguish mito-toxic mechanisms from other cytotoxic events.

Oxidative Stress Assays Promega offers assays for detecting glutathione, measuring the ratio of reduced to oxidized glutathione and detecting changes in ROS as an indicator of cell health or cell signaling events.

Toxicity Pathway Analysis Reporter vectors and cell lines containing response elements for monitoring activity of key cell signaling pathways.

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