Z-VAD-FMK (carbobenzoxy-valyl-alanyl-aspartyl-[O-methyl]- fluoromethylketone) is a cell-permeant pan caspase inhibitor that irreversibly binds to the catalytic site of caspase proteases and can inhibit induction of apoptosis. For inhibition of apoptosis, Z-VAD-FMK should be added at the same time that apoptosis is induced. Z-VAD-FMK is provided at 20mM in DMSO for convenient addition to cell culture or extracts. The peptide is O-methylated in the P1 position on aspartic acid, providing enhanced stability and increased cell permeability. The suggested concentration for use in the anti-Fas mAb-treated Jurkat cell cu...
Expand to Read More »
Z-VAD-FMK (carbobenzoxy-valyl-alanyl-aspartyl-[O-methyl]- fluoromethylketone) is a cell-permeant pan caspase inhibitor that irreversibly binds to the catalytic site of caspase proteases and can inhibit induction of apoptosis. For inhibition of apoptosis, Z-VAD-FMK should be added at the same time that apoptosis is induced. Z-VAD-FMK is provided at 20mM in DMSO for convenient addition to cell culture or extracts. The peptide is O-methylated in the P1 position on aspartic acid, providing enhanced stability and increased cell permeability. The suggested concentration for use in the anti-Fas mAb-treated Jurkat cell culture model system is 20μM.
For more information, see the Protocols & Applications Guide.
« Collapse Content
Caspase Inhibitor Z-VAD-FMK, 20mM
Caspase Inhibitor Z-VAD-FMK
Caspase Inhibitor, Z-VAD-FMK
Store at –20°C protected from light and moisture.
For product intended use please see Patents & Disclaimers tab.
G7231, G7232 For Research Use Only. Not for Use in Diagnostic Procedures.
Your country is set to Korea, Republic Of. Your language is set to 한국어. Please select the language that will best suit your needs:
This is correct, continue to site »
I need additional help