Promega Corporation

Selecting Cell-Based Assays for Drug Discovery Screening

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Abstract

Promega produces a complete portfolio of homogeneous "add-mix-measure" assays. Choosing a cell-based screening method requires understanding the endpoint measured, the correlation with cell viability and the limitations of the assay chemistries. Here we provide recommendations for characterizing a model assay system, describe some of the factors to consider when choosing cell-based assays for automated systems and show examples of multiplexing cell-based assays.

Cell Notes 13, 16–21.

Terry Riss, Rich Moravec and Andrew Niles

Promega Corporation
Publication Date: 2005

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